Toxin, derived from the venom of the spider can replace modern drugs from erectile dysfunction, believe the authors of the respective articles in the journal of Sexual Medicine. Toxin called PnTx2-6, just treats age-related erectile dysfunction, at least in rodents.
This poison was found in the body of the spider Phoneutria nigriventer (Brazilian spider-soldier). Its bite is very painful, and if a spider bites a man, does not exclude the development of priapism - a long, painful and not associated with sexual arousal erection.
Just, evidence of similar problems and has prompted scientists to study the properties of the toxin PnTx2-6 as a means of affecting sexual function. As the experiments showed, the toxin has improved the quality of erections in rodents with diabetes and hypertension. Recently, scholars in the face of Kenya nuns from the University of health Sciences Georgia have successfully tested the toxin in aging animals.
Viagra and other drugs work by blocking the enzyme PDE5. In order to have an erection, the body is releasing nitric oxide, which relaxes smooth muscles of the arteries in the penis, allowing the blood vessels to expand.
And the signal molecule cGMP keeps the muscles in a relaxed state. Moreover, PDE5 reduces the concentration of cGMP, and therefore, the erection will not last forever. But when excess PDE5 erection does not occur. By blocking the enzyme, PDE5 inhibitors solve the problem. However, this does not work with approximately 30% of patients.
The toxin acts differently: he triggers the release of nitric oxide, directly relaxing the muscles. How the toxin will behave in the human body, scientists don't know yet. A synthetic version of the toxin is already there. Now I have to test it for side effects.
Source:
here
No comments:
Post a Comment